Calcium acetate
Calcium acetate.JPG

Calcium acetate

CLINICAL USE

Phosphate binding agent

DOSE IN NORMAL RENAL FUNCTION

1–4 tablets, 3 times daily

PHARMACOKINETICS

  • Molecular weight                           :158.2
  • %Protein binding                           :–
  • %Excreted unchanged in urine     : –
  • Volume of distribution (L/kg)       :–
  • half-life – normal/ESRD (hrs)      :–

    DOSE IN RENAL IMPAIRMENT

    GFR (mL/MIN)

  • 20 to 50     : Dose as in normal renal function. Titrate to response
  • 10 to 20     : Dose as in normal renal function. Titrate to response
  • <10           : Dose as in normal renal function. Titrate to response

    DOSE IN PATIENTS UNDERGOING RENAL REPLACEMENT THERAPIES

  • CAPD                :Unknown dialysability. Dose as in normal renal function
  • HD                     :Unknown dialysability. Dose as in normal renal function
  • HDF/high flux   :Unknown dialysability. Dose as in normal renal function
  • CAV/VVHD      :Unknown dialysability. Dose as in normal renal function

    IMPORTANT DRUG INTERACTIONS

    Potentially hazardous interactions with other drugsCan impair absorption of some drugs, e.g. iron, ciprofloxacin

    ADMINISTRATION

    Reconstition

    Route

    Oral

    Rate of Administration

    Comments

    Take tablets with meals

    OTHER INFORMATION

    Calcium acetate (anhydrous): calcium content per gram = 250 mg (6.2 mmol).



    See how to identify renal failure stages according to GFR calculation

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